Clinical Applications:
Supports Healthy Weight Management
Promotes Gut Barrier Function
Promotes Intake of Less Calories
SupportsReduction of Body Fat Mass                                               Product Information:
At the turn of the 20th century, Nobel Prize laureate Ilya Metchnikov introduced the concept that bacteria in yogurt can help neutralize gut pathogens, which may, in turn, support longevity. Since then, the role of beneficial bacteria in human health has become well established in scientific literature and continues to evolve. In 2002, a working group of experts from the Food and Agriculture Organization (FAO) of the United Nations and the World Health Organization (WHO) defined probiotics as “live strains of strictly selected microorganisms which, when administered in adequate amounts, confer a health benefit on the host. Clinical studies have suggested that supplemental probiotics may positively affect a wide range of health concerns, including gastrointestinal issues, allergies, immune support, and weight management. Epithelial integrity is key to the function of the gastrointestinal tract. According to in vitro and animal research, disturbances to this integrity appear to be linked to metabolic disorders. Total NutriCare packages MegaFlora Lean capsules in sealed, nitrogen-purged blister packs to protect against factors known to compromise probiotic stability, such as heat, moisture, and oxygen. Additionally, to support resistance to low pH and optimize delivery of microorganisms to the small intestine, MegaFlora Lean uses caps gastro-resistant capsules. These specially designed, innovative capsules slow exposure of active ingredients to stomach acid, promoting a more targeted release.
Mega Flora Lean features a vegetarian, gluten-free, and dairy-free formula containing the patented HOWARU® Shape Bifidobacterium animalis subsp. lactis B420 probiotic strain. This probiotic has been proven to be safe, effective, and well-tolerated. It supports healthy body composition by enhancing gut barrier function, aiding in the reduction of body fat mass, and promoting reduced calorie consumption.
In animal research, the potential benefits of B420 in reducing high-fat, diet-induced body weight gain and diabetes were studied. The results showed a reduction in fat mass and improved glucose tolerance in both obese and diabetic mice. Additionally, reduced intestinal mucosal adherence and decreased levels of plasma lipopolysaccharide suggested a mechanism involving reduced translocation of gut microbes.